Many guideline failures are not failures of evidence alone, they are failures of process. Economic constraints, logistical complexity, and political realities exert a profound influence on guideline development, yet these forces are rarely discussed in the methodology literature despite being obvious to anyone who has lived through a guideline development process. The previous posts …

Continue reading “Clinical Guideline Development (Part 5): Why Guidelines Fail – The Structural Forces That Undermine Credibility, Stall Timelines, and Compromise Independence”