In 1951, the United States Air Force had a question that could not be answered by experiment: how many atomic bombs would be required to significantly disrupt U.S. industrial capacity under nuclear attack? There were no historical precedents to draw on, no experiments to run, no datasets to analyse. All the Air Force had …
This is the first in a five-part series on the science and methodology behind clinical practice guidelines and consensus statements. The series “From Hippocrates to Delphi” is named for the arc that connects the earliest attempts to codify medical practice to the structured consensus methods we use today. Hippocrates gave us the idea that clinical …